New index to select more disease-resistant cattle hailed a world first

World first for beef with new index to select disease-resistant cattle

Beef
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Angus Australia and the CSIRO have combined to develop a breeding index value to select animals with superior immune systems.

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In what's been hailed as a world first for the beef industry, research by Angus Australia and CSIRO has resulted in the development of the breeding index value, ImmuneDEX.

Announced at the Angus through the Ages National Conference in Albury, ImmuneDEX is a genetic description of an animal's ability to react to an immune system challenge (i.e. disease).

Over the course of a number of years, Angus Australia and CSIRO have worked in collaboration to immune competence test calves from the Angus Sire Benchmarking Program (ASBP), with the research co-funded by the Australian Lot Feeders Association via Meat and Livestock Australia.

To develop the ImmuneDEX breeding value, immune competence phenotypes were collected on about 3000 Angus steers and heifers at weaning and analysed.

This information, combined with genotypes (DNA profiles) was analysed to determine genetic parameter estimates (heritabilities and correlations) and to produce research breeding values for immune competence.

Christian Duff, Angus Australia strategic projects manager, said the work done to develop the ImmuneDEX breeding value was a successful collaborative effort between those at CSIRO and Angus Australia.

"It is has been excellent working in collaboration with CSIRO on this research," Mr Duff said

"While there is still more research to be undertaken to further develop the ImmuneDEX breeding value and validate its potential to deliver health benefits to industry, this development is a definite stride for Angus breeders and the broader beef industry."

Furthermore, on a subset of 900 steers from this study, disease incidence during feedlot feeding was examined.

Findings showed that animals with a superior immune competence phenotype had significantly lower health related costs and mortality rates. Importantly, the genetic strategy is expected to assist in reducing the use of antibiotics, improving overall welfare and health of the animal, and maintaining consumer confidence.

While still in its early research stages, the information now available through the ImmuneDEX breeding value will assist beef producers make decisions about what the best animals are to breed from into the future with the goal of improving animal health while simultaneously improving productivity.

Dr Brad Hine, research scientist at CSIRO, explained the perspective long term benefits of the ImmuneDEX research findings.

"We know if we continue breeding with a sole focus on production a consequence we will inadvertently increase susceptibility to disease and associated antibiotic use."

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